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Anti-ALB Protein A Scaffold, Biotin-Conjugated (CAT#: AFB-28LY)

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DESCRIPTION CATALOG # SIZE PRICE
Anti-Human HSA Protein A scaffold, Biotin-Conjugated AFB-28LY 1mg Please Inquiry

PRODUCT INFORMATION

  • Product Overview
  • The Anti-HSA Protein A Scaffold molecule binds with high affinity to native albumin from human, mouse and rat serum. The Anti-HSA Protein A Scaffold molecule can be used as capture reagent or detection reagent in ELISA. It is also well suited for affinity chromatography and depletion of HSA from human serum. The Biotin-Conjugated Anti-HSA Protein A Scaffold molecule is biotinylated at a unique C-terminal cysteine using a maleimide-biotin reagent, facilitating immobilization on various streptavidin coated solid supports.
  • Species Reactivity
  • human
  • Expression Host
  • E. coli
  • Applications
  • ELISA, Affinity chromatography.
  • Specific Activity
  • Anti-HSA Protein A scaffold molecule binds to native human serum albumin (HSA) and also to serum albumin of mouse and rat origin.
  • Molecular Weight
  • 14.0 kDa
  • Storage
  • Short-term storage at +4°C is recommended. For long-term storage, the protein solution should be aliquoted and then stored at -20°C.
    There is no decrease in performance of the biotinylated Protein A Scaffold molecule after 10 repeated freeze and thaw cycles or afte

BACKGROUND

  • Antigen Description
  • Human serum albumin (HSA), a soluble, monomeric protein, is the most abundant protein in human serum. Normal levels are 40-60 mg/ml HSA in blood; however the amount of HSA decreases upon infection. HSA acts primarily as a carrier protein for steroids, fatty acids and thyroid hormones, and it stabilizes extracellular fluid volume. Serum albumin is produced by the liver as pre-proalbumin and it is cleaved twice before secretion.
  • Function
  • Serum albumin, the main protein of plasma, has a good binding capacity for water, Ca(2+), Na(+), K(+), fatty acids, hormones, bilirubin and drugs. Its main function is the regulation of the colloidal osmotic pressure of blood. Major zinc transporter in plasma, typically binds about 80% of all plasma zinc.
  • Synonyms
  • PRO0883; PRO0903; PRO1341; DKFZp779N1935; ALB; serum albumin; OTTHUMP00000160370; OTTHUMP00000196832; OTTHUMP00000220435; OTTHUMP00000220436; OTTHUMP00000220438; OTTHUMP00000220439; growth-inhibiting protein 20; cell growth inhibiting protein 42

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